{"id":4722,"date":"2023-10-02T21:29:20","date_gmt":"2023-10-02T12:29:20","guid":{"rendered":"https:\/\/www.aureo.co.jp\/?p=4722"},"modified":"2023-10-03T17:03:29","modified_gmt":"2023-10-03T08:03:29","slug":"5937029","status":"publish","type":"post","link":"https:\/\/www.aureo.co.jp\/en\/patent\/5937029\/","title":{"rendered":"TRAIL expression enhancer &#8211; Japan (Patent No. 5937029)"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium\" style=\"font-size: 16px;\" src=\"https:\/\/www.aureo.co.jp\/wp-content\/uploads\/2020\/07\/JapanTokkyo5937029-1.png\" width=\"496\" height=\"702\" \/><\/p>\n<p class=\"Blue_Sub\">Patent Details<\/p>\n<div>\n<dl class=\"tbl\">\n<dt>\n<div>Patent No.<\/div>\n<\/dt>\n<dd>No. 5937029<\/dd>\n<\/dl>\n<dl class=\"tbl\">\n<dt>\n<div>Registration Date<\/div>\n<\/dt>\n<dd>May 20, 2016<\/dd>\n<\/dl>\n<\/div>\n<p>The body has an immune function that produces &#8220;anti-cancer substances&#8221; on its own to suppress the growth of cancer. Some of the &#8220;anti-cancer substances&#8221; produced may damage not only cancer cells but also normal cells, just like anti-cancer drugs in the treatment.<\/p>\n<p>However, &#8220;trails&#8221; among such substances have little effect on normal cells and selectively lead cancer cells to apoptosis as an inhibitory effect on cancer growth.<\/p>\n<p>We tested whether Aureobasidium (black yeast) culture fluid (hereafter referred to as &#8220;Aureo culture fluid&#8221;) is useful as an agent that enhances this &#8220;trail&#8221;.<\/p>\n<p>As a result, it was confirmed that \u03b2-glucan from barley and \u03b2-glucan from baker&#8217;s yeast hardly enhanced the expression of trails in humans and mice, whereas Aureobasidium culture fluid enhanced the production of trails.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>Patent Details Patent No. No. 5937029 Registration Date May 20, 2016 The body has an immune function that produces &#8220;anti-cancer substances&#8221; on its own to suppress the growth of cancer. Some of the &#8220;anti-cancer substances&#8221; produced may damage not only<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_locale":"en_US","_original_post":"https:\/\/www.aureo.co.jp\/?p=4100","footnotes":""},"categories":[9],"tags":[],"class_list":["post-4722","post","type-post","status-publish","format-standard","hentry","category-patent","en-US"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/posts\/4722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/comments?post=4722"}],"version-history":[{"count":2,"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/posts\/4722\/revisions"}],"predecessor-version":[{"id":4848,"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/posts\/4722\/revisions\/4848"}],"wp:attachment":[{"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/media?parent=4722"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/categories?post=4722"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.aureo.co.jp\/wp-json\/wp\/v2\/tags?post=4722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}